Foxa3 macrophage
WebFOXA3. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC. Assigned HPA protein class (es) for the encoded ... WebMar 21, 2024 · FOXA3 (Forkhead Box A3) is a Protein Coding gene. Diseases associated with FOXA3 include Adult Acute Monocytic Leukemia and Maturity-Onset Diabetes Of …
Foxa3 macrophage
Did you know?
WebAug 11, 2006 · The Foxa subfamily of winged helix/forkhead box (Fox) transcription factors has been the subject of genetic and biochemical study for over 15 years.During this time its three members, Foxa1, Foxa2 and Foxa3, have been found to play important roles in multiple stages of mammalian life, beginning with early development, continuing during … WebDec 12, 2024 · Overall, these data suggest that FOXO3 inactivation in macrophages enhances IL-10 expression, leading to a modulated …
WebThe relative mRNA levels of FOXA3, HNF1A, ZFHX3, and MYC in the Model, si-NC, si-FOXA3-1,, and si-FOXA3-2 group measured by RT-PCR. Knockdown of FOXA3 markedly decreased the relative mRNA levels of FOXA3 and HNF1A/MYC, while dramatically increased the relative mRNA levels of ZFHX3. ** p < .01 VS Huh-6 group, indicating the … WebObjective: To determine the role of hepatic FOXA3 (forkhead box A3) in lipid metabolism and atherosclerosis. Approach and Results: Hepatic FOXA3 expression was reduced in …
WebFOXA3 is a transcription factor involved in the macrophage cholesterol efflux and macrophage reverse cholesterol transport reducing the atherosclerotic... DOAJ is a unique and extensive index of diverse open access journals from around the world, driven by a growing community, committed to ensuring quality content is freely available online for ... WebNational Center for Biotechnology Information
WebMar 8, 2016 · Foxa3 is required for GC-mediated adipogenic gene programs in preadipocytes and for lipid metabolism gene programs in mature adipocytes. ( A) Heatmap of adipogenic genes in undifferentiated primary SVF or 10T1/2 cells treated with differentiation mixture with or without Dex.
WebAblation of FOXA3 protects against the development of obesity and insulin resistance in aged mice on a high fat diet and improves lifespan ( 6 ). Another proposed mechanism … dance series to watchWebJun 24, 2011 · These studies suggest that FOXP3 + macrophages can support and promote tumour growth. In summary, this study describes a unique population of … dance school tbilisiWebApr 19, 2024 · FOXA3 Polymorphisms Are Associated with Metabolic Parameters in Individuals with Subclinical Atherosclerosis and Healthy Controls—The GEA Mexican Study. ... CEBP is a family of transcriptional factors involved in the macrophage activation. One of these factors, the CEBP beta, regulates several cytokines such as IL-1B, IL-6, IL-8, IL … dance schools in wilmington ncWebSep 15, 2014 · Significance. This paper reports that the transcription factor forkhead box protein A3 (Foxa3) is directly involved in the development of age-associated obesity and insulin resistance. Mice that lack the Foxa3 gene remodel their fat tissues, store less fat, and burn more energy as they age. These mice also live significantly longer. birdwell roundabout mapdance school stories onlineWebFeb 1, 2014 · Methods: FOXA3 was identified in airways from patients with asthma and chronic obstructive pulmonary disease. We produced transgenic mice conditionally expressing Foxa3 in airway epithelial cells and developed human bronchial epithelial cells expressing Foxa3. dances found in zimbabweWebJul 1, 2024 · FOXA3 is induced by ER stress and transcriptionally activated by XBP1s. • FOXA3 overexpression or knockout affected TM-induced lipid accumulation. • FOXA3 deficiency in liver ameliorates diet- or genetic-induced NAFLD. • FOXA3 directly regulates Per1 transcription to govern lipid synthetic genes. • birdwell school academy