WebAug 30, 2024 · Background The lipid scavenger receptor cluster of differentiation 36 (CD36) has been shown to have a pro-metastatic function in several cancers. Adipose tissue, a favorable site for peritoneal metastasis (PM) from gastric cancer (GC), promotes this process by providing free fatty acids (FFAs); however, the role of CD36 in PM … WebWe found that CD36 was selectively upregulated in intrautumoral T reg cells as a central metabolic modulator. CD36 fine-tuned mitochondrial fitness via peroxisome proliferator …
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WebGet better batch-to-batch reproducibility with a recombinant antibody. Anti-CD36 antibody [EPR22512-58] (ab252923) Research with confidence – consistent and reproducible results with every batch. Long-term and scalable supply – powered by recombinant technology for fast production. Success from the first experiment – confirmed specificity ... WebCD36 is a class B scavenger receptor composed of short amino-terminal and carboxy-terminal cytoplasmic domains, two transmembrane domains, and a large glycosylated extracellular domain (1-4). The CD36 receptor has many diverse ligands and cellular functions and is expressed by multiple cell types, including monocytes, macrophages, …
WebCD36 (also known as scavenger receptor B2) is a multifunctional receptor that mediates the binding and cellular uptake of long-chain fatty acids, oxidized lipids and phospholipids, … WebCD36 is a glycoprotein expressed at the cell surface of several differentiated cells. It possesses two transmembrane segments leading to two short cytoplasmic tails (N- and …
WebCD36 is a multifunctional molecule involved in several diseases, including cancer, metabolic diseases, Alzheimer's disease, and infection. CD36 plays a critical role in lipid uptake, immunological recognition, inflammation, … WebThis study is significant because it will have a positive translational impact on breast cancer therapy with reduced toxicity. We will continue to test our hypothesis through two specific aims and the integration of a novel technological platform: Aim 1a will identify breast cancer subtypes that are sensitive to the three recombinant proteins ...
CD36 (cluster of differentiation 36), also known as platelet glycoprotein 4, fatty acid translocase (FAT), scavenger receptor class B member 3 (SCARB3), and glycoproteins 88 (GP88), IIIb (GPIIIB), or IV (GPIV) is a protein that in humans is encoded by the CD36 gene. The CD36 antigen is an integral membrane protein … See more Primary In humans, rats and mice, CD36 consists of 472 amino acids with a predicted molecular weight of approximately 53,000 Da. However, CD36 is extensively glycosylated and … See more In humans, the gene is located on the long arm of chromosome 7 at band 11.2 (7q11.2 ) and is encoded by 15 exons that extend over more than 32 See more The protein itself belongs to the class B scavenger receptor family which includes receptors for selective cholesteryl ester uptake, See more CD36 plays a role in the regulation of angiogenesis, which may be a therapeutic strategy for controlling the spread of cancer. Some data from in vitro and animal studies suggested that fatty acid uptake through CD36 may promote cancer cell migration and … See more CD36 is found on platelets, erythrocytes, monocytes, differentiated adipocytes, skeletal muscle, mammary epithelial cells, spleen cells and some skin microdermal endothelial cells. See more Malaria Infections with the human malaria parasite Plasmodium falciparum are characterized by sequestration of erythrocytes infected with mature forms of the parasite and CD36 has been shown to be a major sequestration … See more CD36 has been shown to interact with FYN. See more
WebAffiliations 1 Department of Medicine and Therapeutics, and Centre for Cardiovascular Genomics and Medicine, The Chinese University of Hong Kong (CUHK), HKSAR, China. [email protected].; 2 CAS Key Laboratory of Tissue Microenvironment and Tumor, Laboratory of Molecular Cardiology, Shanghai Institute of Nutrition and Health, University … datatool contact numberWebCD36 is a membrane glycoprotein present on platelets, mononuclear phagocytes, adipocytes, hepatocytes, myocytes, and some epithelia. On microvascular endothelial … marzia hotel scandicciWebNonetheless, CD36 blockade before tetramer staining resulted in a marked reduction in staining events in each case, revealing residual populations of tetramer + T cells. Thus, CD36 blockade should facilitate ex vivo analysis of CD1d-restricted cells with type II antigens, such as sulfatide and LPC . marzia ingrassia unipaWebCD36 (fatty acid translocase, FAT) is an 88 kDa, ditopic glycosylated protein that belongs to the class B family of scavenger receptors. CD36 is expressed by most resting marginal zone B cells but not by follicular and B1 B cells, and is rapidly induced on Follicular B cells in vitro upon TLR and CD40 stimulation. datatool blender importerWebFeb 17, 2024 · CD36 was found to be upregulated on T reg cells in multiple tumors types, but the therapeutic effects of CD36 blockade were only explored in melanoma and other subcutaneous models 2. marzia lachelloWebJul 9, 2024 · CD36 promotes tumor metastasis. Tumor metastasis-initiating cells (MICs) represent a rare and unique population of cells derived from primary tumors that can … datatool battery conditionerWebCited in 100 publications. View Rabbit Polyclonal anti-CD36 Antibody - BSA Free (NB400-144). Validated Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P. Validated Species: Human, Mouse, Rat + more. Validated by: Biological Strategies, Orthogonal Strategies. Sample size available. Range of directly conjugated antibodies available. marzia lecchi